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Brave the challenges of sequencing

At QIAGEN Bioinformatics, we shape our solutions to meet the specific demands of our customers, who require efficiency and confidence when processing large amounts of data. Our RNA sequencing bioinformatics solution has been carefully designed to deliver data integrity and quality, and to drive confidence in biological interpretation.

Streamline your research and power through it

Understanding the biology buried in raw sequencing files is a significant challenge for scientists. Data must be examined within the context of complex biological processes, and rapidly increasing throughput makes analyses time and labor intensive. Our RNA-seq solution is an innovative application addressing the throughput bottlenecks in academic research. It provides an intuitive user experience as the solution integrates data analysis and biological interpretation.

Using IPA and the Upstream Regulator Analysis module, with just seven cases, we found two really strong predictors for differences between the platinum-sensitive and the platinum-resistant patients…

John Martignetti, Associate Professor,

The Icahn School of Medicine at Mount Sinai.  Learn more…

Publish novel findings

Publishing is paramount to academic success. Our user-friendly bioinformatics solution with integrated workflow accelerates your time to submission in peer-reviewed journals.

Ingenuity Pathway Analysis (IPA) is one of the key components of our RNA-seq solution and has been recognized in the industry standard for ‘omics’ data analysis. It has been broadly adopted by academic researchers and cited in more than 14,000 peer‐reviewed publications.

Bioinformatics tools for Somatic Cancer Research


Secondary NGS Data Analysis

Variant Filtering

Variant Interpretation and Reporting

Clinical Testing Services

HGMD Professional

Solve more cases faster, with data you can trust using HGMD Professional, the de facto standard resource for identifying inherited disease-causing mutations.

Founded and maintained by the Institute of Medical Genetics at Cardiff University in 1993, HGMD Professional contains over 260,000 manually curated mutation reports from over 2,600 peer-reviewed journals. Updated quarterly, HGMD Professional is licensed exclusively through QIAGEN and offers clinical research labs pipeline access to the latest reports of all published inherited disease mutations.

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QCI Analyze

Simplify and standardize the processing and analysis of NGS data with QIAGEN Clinical Insight (QCI®) Analyze, scalable software fueled by powerful algorithms to seamlessly convert FASTQ files to high quality variant lists.

Compatible with all major sequencing platforms, QCI Analyze efficiently converts FASTQ files to VCF files through preconfigured, comprehensive and scalable pipelines controlled by role-based permissions. The software uses powerful, globally recognized algorithms to pinpoint even the most difficult-to-detect variants and fusions.

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Ingenuity Variant Analysis

Quickly prioritize variants with Ingenuity Variant Analysis, a web-based application combining analytical tools and expert-curated content from the QIAGEN Knowledge Base to help you filter down to a small, targeted subset of compelling candidates.

Connected to the industry’s most expansive collection of biological and clinical findings, sourced from over two decades of manual data and literature curation from more than 40 scientific and clinical databases, Ingenuity Variant Analysis leverages powerful algorithms and dynamic filtering to triage variants using both published evidence and your lab’s own experiential knowledge.

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QCI Interpret

When it comes to classifying rare and complex variants, having access to as much data as possible is critical for accurately identifying and evaluating variants that could potentially contribute to the incidence of disease.

QCI Interpret is clinical decision support software that reproducibly translates highly complex next-generation sequencing (NGS) data into concise, clinician-ready reports, using current clinical evidence and all 28 criteria of the ACMG/AMP published guidelines for the assessment of variants in genes associated with Mendelian diseases.

Connected to the QIAGEN Knowledge Base, a continuously updated and manually curated resource spanning across 40 public and proprietary databases, QCI Interpret empowers your lab with the insight only two decades of expert curation can deliver.

The software provides full transparency to review the criteria and evidence supporting each classification and allows you to customize the final report to include the variants, interpretations and references specified throughout the assessment.

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Related Resources

QIAGEN Clinical Testing Services

Accelerate time to launch with clinical testing and informatics services focused on expanding and differentiating your test menu.

QIAGEN Clinical Testing Services deliver complete end-to-end testing solutions, fully customizable and capable of supporting a broad range of indications both now and in the future.

  • On-demand variant scoring and classification services Launch new test offerings faster while scaling your existing variant scientist team.
  • Customized reporting solutions Provide unique and differentiated report layouts for brand recognition.
  • Pipeline development and optimization Rely on one partner to monitor, develop and train your bioinformatics team.



Start streamlining your research

Do you want know more? Read articles and watch video. 

Rare & Undiagnosed Diseases

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Inherited Diseases

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Hereditary Cancer

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