Sample to Insight for Oncology
Accelerate your time-to-result in NGS oncology testing
Does your lab need a fast, cost-effective, ultra-precise workflow for oncology NGS testing?
Targeted next-generation sequencing (NGS) is an ideal tool for studying the genetic basis of cancer, facilitating the survey of large numbers of targets (potential variants) in parallel, while also offering high sensitivity. QIAGEN’s new barrier-breaking Sample to Insight Oncology Solution combines targeted DNA and multimodal pan-cancer panels, one of the fastest and cheapest secondary analysis in the market and trusted variant interpretation and reporting software powered by augmented molecular intelligence.
Sample to Insight for Oncology:
Meet us at CGC 2023 | Booth #12
This year at the Cancer Genomics Consortium (CGC) Annual Meeting, QIAGEN will be at booth #12 premiering our new Sample to Insight workflow for oncology NGS testing.
Build your workflow with four NGS steps
Step 1: Library Preparation
QIAseq panels
Step 2: Sequencing
Sequencer of your choice
Step 3: Data Analysis
QCI Secondary Analysis
Step 4: Interpretation and Reporting
QCI Interpret for Oncology
Panels
QIAseq Targeted DNA Pro and Multimodal Pan Cancer Panels
QIAseq Targeted DNA Pro and Multimodal Pan Cancer Panels set a new standard for NGS genotyping. Major innovations within this chemistry provide improved ease-of-use, efficiency and expanded variant analysis to simplify and speed-up your NGS workflows.
- Complete, uniform target coverage – single-tube enrichment for up to 20,000 DNA targets (and an
additional 8,000 RNA targets for multimodal) staggered placement of primers across the target region
ensures high uniformity (>99%) and complete coverage.
- High compatibility with challenging samples – works with FFPE samples, plasma/serum, fresh or frozen
tissue, cell lines, liquid biopsies with a minimum DNA input requirement as low as 10 ng.
- Single-day, automation-friendly library preparation – go from sample to sequencing-ready library in 8 hours or less with minimum hands-on time.
- Customization made easy – boost any cataloged panel with additional content if something is missing or design a custom panel using either our flexible GeneGlobe custom builder or expert design service.
- Pan-cancer profiling with multimodal approach – comprehensive genomic profiling workflow for simultaneous detection ofDNA variants, RNA fusions and TMB/MSI status in solid tumors and heme malignancies.
Enables sample to sequencing-ready
libraries in less than 6 hours for detection
of SNVs, small indels, CNVs and loss of
heterozygosity (LOH).
Enables detection of variant allele frequency down to 0.1% VAF from cfDNA
with >99% specificity.
Enables simultaneous enrichment and
profiling of DNA variants, RNA fusions
and gene expression levels from one
sample.
NGS Secondary Analysis
QCI Secondary Analysis with LightSpeed
LightSpeed is a new module for QIAGEN CLC Genomics Workbench Premium that empowers laboratories to perform NGS secondary analysis with high accuracy at unprecedented runtimes.
LightSpeed processes FASTQ files to produce VCF files containing single nucleotide variants (SNV), insertion–deletion mutation (InDel) and structural variant (SV) calls. The module is deployable using local computers or Amazon Web Services (AWS®) cloud and performs quality and adapter trimming, read mapping, deduplication, local realignment, quality control and variant calling.
Variant Interpretation and Reporting
QCI Interpret for Oncology
QCI Interpret is NGS variant interpretation and reporting software powered by augmented molecular intelligence that helps labs not only make faster decisions—but the right decisions.
Connected to the exclusive QIAGEN Knowledge Base, the industry’s most comprehensive, manually curated resource updated weekly, QCI Interpret delivers variant-specific, scientific evidence in context of phenotype or diagnosis. Interactive filters prioritize variants and proprietary algorithms transparently compute AMP/ASCO/CAP and ACMG/AMP variant classifications, enabling users to generate evidence-based reports with efficiency, confidence, and reproducibility.
Resources
Contact us
Let us help you optimize your NGS analysis pipeline. Our services team is here to answer your questions and help you get from sample to final report in less time, for less money.
Disclaimers:
The QIAseq Targeted DNA Pro Panels and Pan-cancer Multimodal Panels are intended for molecular biology applications. These products are not intended for the diagnosis,
prevention or treatment of disease.
LightSpeed is software module to support NGS secondary analysis. The software is NOT intended as a primary diagnostic tool by physicians or to be used as a substitute for professional healthcare advice. Each laboratory is responsible for ensuring compliance with applicable international, national, and local clinical laboratory regulations and other specific accreditations requirements.
QCI Interpret is an evidence-based decision support software intended as an aid in the interpretation of variants observed in genomic next-generation sequencing data. The software evaluates genomic variants in the context of published biomedical literature, professional association guidelines, publicly available databases, annotations, drug labels, and clinical trials. Based on this evaluation, the software proposes a classification and bibliographic references to aid in the interpretation of observed variants. The software is NOT intended as a primary diagnostic tool by physicians or to be used as a substitute for professional healthcare advice. Each laboratory is responsible for ensuring compliance with applicable international, national, and local clinical laboratory regulations and other specific accreditations requirements.