Latest improvements for QIAGEN OmicSoft Suite

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OmicSoft Suite v12.8 release update

QIAGEN® OmicSoft Suite v12.8 is now available for download and installation. This update brings several improvements, particularly for customers using AWS for NGS Cloud analysis.

If you connect to a dedicated OmicSoft Server instance, remind your administrator to update your OmicSoft Server. The OmicSoft Studio client will prompt you to update.

Reach out to your OmicSoft Server administrator and have your ArrayServer.cfg file reviewed for the latest recommended configuration parameters, including updated Amazon Machine Images (“AMIs”) for cloud-based next-generation sequencing (NGS) data analysis, support for faster downloads of FASTQ files from SRA, and user authorization options.

New features

AWS improvements

We have made several improvements to the OmicSoft Server cloud integration logic. These include shorter instance startup times, capacity reservation, improved Elastic Block Store (EBS) volume provisioning, and support for Elastic File System (EFS). To learn more about implementing these changes, please visit the OmicSoft knowledge page. Please note that using EFS support and capacity reservation may result in additional costs, so please use these features carefully.

These changes require the latest OmicSoft AMIs, so we recommend setting the parameter Ami=Latest in the [Cloud] section of your ArrayServer.cfg file. Alternatively, you can retrieve our latest AMIs and update them with the necessary Linux packages.

Updated gene annotations

In OmicSoft Studio, you can now browse, filter, and explore genes for popular Land gene models based on curated gene information for molecule type, protein evidence, subcellular location, function, chemical activators, and gene expression pattern. Learn more about these extended gene annotations at this knowledge page.

Other improvements of interest

• From the Gene Distribution View in Lands, you can select one or more genes and click Browse Genes to execute a search immediately.
• Improved log communication mechanism between cloud and server instances.
• Updates to CRISPR Gene Dependency views
• The metadata field “mutation frequency” now is labeled “Variant Allele Fraction”.
• Detailed server logging can now be enabled or disabled for gRPC/SFTP connections without needing to restart the OmicSoft Server application.
• Various bug fixes, as enumerated in the change log.

Compatibility

OmicSoft Suite v12.8 components are compatible with previous OmicSoft Suite v12 components.

• OmicSoft Server v12.8 is compatible with OmicSoft Studio v12.1 to v12.7
• OmicSoft Studio v12.8 is compatible with OmicSoft Server v12.1 to v12.7
• oshell v12.8 is compatible with OmicSoft Server v12. to -v12.7
• Land Explorer v.4.4 is compatible with OmicSoft Server v12.1 to v12.8

Installation and update instructions

OmicSoft Server is installed by executing the v12.8 OmicSoft Server MSI on Windows® or OmicSoftServiceUpdater.exe on Linux installations.

OmicSoft Studio is installed by either updating from previous OmicSoft Studio v12 versions using OmicSoft Launcher (will be prompted) or new installations with the MSI.