Discovery Knowledge Base 1.0

What’s new in the QIAGEN Discovery Knowledge Base and Discovery KB+ 2026.1 release

Software and documentation changes:

• Biomedical Knowledge Base has been renamed to Discovery Knowledge Base (Discovery KB or DKB)
  • Python and R clients have been updated to reflect this change
  • The REST API endpoint address has been updated to reflect this change
• New Python and R clients must be used to access the latest data version via the API
• Updated tutorial and webinar notebooks with fixes

Content changes:

• Coverage
  • Added NLP-processed relationships from FAERS, patent, grant and publication sources
    • These relationships are marked as "AI Automated Review Findings" under the "data_acquisition_method" property
  • Added 9 ontology nodes that were previously cited but not described in the content
  • Added primary references to finding metadata for a subset of ClinVar findings which previously included only secondary references
  • Added localization values under "relationship_type" for gene location relationships that previously did not include
• Naming
  • The "synonyms" table now includes acronyms for entities
  • The "variation_metadata" content now includes mapping of variants to dbSNP IDs
  • 700 new "Biocrates_id" values were included
• Alignment and integration
  • Eliminated a small number of redundant names for cell types
  • Corrected redundant descriptions of metadata for 50 findings
  • Corrected 16 pathway nodes by restoring unintentionally omitted content
  • Corrected overlap between "process_property" and "variation_type"
  • Made minor fixes to property descriptions
  • Reduced the number of molecule nodes where n > 1 for "high_level_node" by 50%
• Neo4j-bio representation:
  • The "curation" attribute for interaction edges was renamed to "data_acquisition_method"
• Tabular representation:
  • Filled in missing values in the "relationship_type_category" column
  • The "project_start_date" and "project_end_date" columns in the "sources" table are now typed as DATE