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QIAGEN Clinical Knowledge Base

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Conquer information overload

The era of next-generation sequencing (NGS) has resulted in an explosion of genetic data and discoveries. Each year, the scientific research community publishes more than two million peer-reviewed articles—a trend that first started in 2012 (1).  This means the world’s genomic knowledge is not only growing, but constantly changing.

The QIAGEN Clinical Knowledge Base helps you stay informed and up-to-date given the exponential growth of literature and continual change in clinical trial availability and therapeutic options. 

Over 20 years of expert curation

Empower your clinical research and testing with the world’s largest, manually curated

knowledge base of clinical and biological findings


curated clinical findings


patient cases analyzed


disease classes covered


citations in publications


articles added per month


MD and PhD level curators

"We value QIAGEN’s commitment to deliver the highest quality of manually curated knowledge for analysis and interpretation of content through its extensive and comprehensive portfolio of solutions that enable accurate and standardized clinical reporting."

Augusto Rendon, PhD
Director of Bioinformatics and Genomics England
The 100,000 Genomes Project

On-demand manual curation 

The information core of QIAGEN Clinical Insights (QCI), the QIAGEN Clinical Knowledge Base is maintained by hundreds of MD and PhD-level certified curators and is ISO 9001-certified for reproducibility.

Content from primary literature is updated daily, with information on clinical trials and approved therapeutics refreshed weekly. The QIAGEN Clinical Knowledge Base enables QCI customers to remain current without the burden and expense of internal manual curation.

White paper

Lab performing expanded carrier screening boosts efficiency by 80%

A high-throughput population screening laboratory was able to save considerable time and effort when using the QIAGEN Clinical Knowledge Base to search for variant-specific articles to satisfy the levels of evidence needed to definitively determine variant classifications. 

QCI Interpret

Expand your clinical interpretation with expert-curated software for variant classification of any assay, covering any indication, on your sequencing platform

QCI Precision Insights

Reimagine your clinical interpretation with same day, expert variant classification services tailored to your oncology panel

Clinical Analysis and Interpretation Services

Leverage the benefits of automation and expert support to improve test turnaround times and clinical reporting capabilities

Hereditary Diseases

Empower clinicians and their patients to make critical and timely healthcare decisions with the latest publications and clinical evidence


Provide oncologists with the best information needed to make timely, educated decisions about their patients’ cancer treatment plans​

Human Gene Mutation Database

Solve more cases faster, with data you can trust using HGMD Professional, the de facto standard resource for identifying inherited disease-causing mutations​

1. The STM Report 2018: An Overview of Scholarly and Scientific Publishing. Retrieved December 15, 2019, from www.stm-assoc.org/2018_10_04_STM_Report_2018.pdf