Transcriptome analysis of pancreatic cancer exosomes

Webinar: Transcriptome analysis of pancreatic cancer exosomes involved in metastatic progression

Pancreatic cancer is one of the most lethal malignancies with a poor prognosis. Liquid biopsies are non-invasive methods for diagnostics to detect early stage cancer resulting in more successful treatment. One liquid biopsy technique is the detection of RNA from tumor-derived exosomes.

In this webinar you can learn how bioinformatics solutions can be used to analyze and interpret RNA-sequencing results from these exosome experiments, providing additional hypothesis on regulatory networks and potential isoforms of biological significance. We’ll examine the transcriptome of pancreatic tumor-derived exosomes that induce the formation of a liver metastatic niche, and demonstrate how our solutions can provide deep biological understanding in this process.

Find out how to:

• Streamline RNA-sequencing alignment and analysis using configured workflows for the fast track to biological interpretation
• Analyze exosome gene expression signatures to pinpoint significant genes associated with early detection of pancreatic cancer
• Identify significantly differentially expressed isoforms and their association to pancreatic cancer
• Generate novel regulatory networks as hypotheses suggesting drivers of the expression changes observed in these tumor producing exosomes to better understand pancreatic cancer drivers