Will you be joining our workshop?
Throughout SOT 2017 you can find us in booth #1812, Exhibit Hall E. You’re also welcome to join our workshop and exhibitor presentation Tuesday, where our speaker, Dev Mistry, will present during lunch.
March 14th, 12:00 p.m. – 1:00 p.m.
Location: Room 340, Baltimore Convention Center
Workshop title & abstract
Investigating Nrf2’s protective role in kidney through transcriptomics and proteomics data interpretation using Ingenuity Pathway Analysis (IPA)
Transcription factor Nrf2 can play a protective role against oxidative stress and nephrotoxic insults. Nrf2’s protective role in kidney is investigated by comparing Nrf2 knockout mice to their wild-type counterparts. These mice are also treated with CDDO-me, an Nrf2 inducer. Here we analyze and interpret these published (Shelton LM et al., PMID 26422507) transcriptomics and proteomics datasets using IPA. IPA identifies Nrf2 as the key upstream regulator accompanying the activation of detoxification-related pathways and biological processes. Comparison analysis of transcriptomics and proteomics datasets shows enrichment of similar pathways and cellular processes, and highlights IPA as a powerful tool for multi-omics tox analysis.
We hope to see you March 12-16, 2017 in Baltimore Convention Center, MD (1 W Pratt St, Baltimore, MD 21201)
You can find informations about SOT 2017 in their official website here: http://www.toxicology.org/events/am/AM2017/index.asp