BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Bioinformatics Software | QIAGEN Digital Insights - ECPv6.15.17.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Bioinformatics Software | QIAGEN Digital Insights
X-ORIGINAL-URL:https://staging.digitalinsights.supremeclients.com
X-WR-CALDESC:Events for Bioinformatics Software | QIAGEN Digital Insights
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Halifax
BEGIN:DAYLIGHT
TZOFFSETFROM:-0400
TZOFFSETTO:-0300
TZNAME:ADT
DTSTART:20220313T060000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0300
TZOFFSETTO:-0400
TZNAME:AST
DTSTART:20221106T050000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0400
TZOFFSETTO:-0300
TZNAME:ADT
DTSTART:20230312T060000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0300
TZOFFSETTO:-0400
TZNAME:AST
DTSTART:20231105T050000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0400
TZOFFSETTO:-0300
TZNAME:ADT
DTSTART:20240310T060000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0300
TZOFFSETTO:-0400
TZNAME:AST
DTSTART:20241103T050000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;VALUE=DATE:20231101
DTEND;VALUE=DATE:20231106
DTSTAMP:20260410T181604
CREATED:20231030T163815Z
LAST-MODIFIED:20241024T182948Z
UID:10000698-1698796800-1699228799@staging.digitalinsights.supremeclients.com
SUMMARY:ASHG 2023
DESCRIPTION:This year at the American Society for Human Genetics (ASHG) 2023 Annual Meeting\, QIAGEN will be showcasing our Sample to Insight solutions for human genetics at booth #902. Learn more about our products and solutions and receive complimentary demos of our bioinformatic software and databases. Our experts will be available to chat with you and answer any questions you may have. We look forward to seeing you at ASHG 2023.
URL:https://staging.digitalinsights.supremeclients.com/webinars-and-events/ashg-2023/
LOCATION:Washington\, DC\, United States
CATEGORIES:Clinical,Event
ATTACH;FMTTYPE=image/jpeg:https://staging.digitalinsights.supremeclients.com/wp-content/uploads/2024/05/S_5632_GEN_DC_Cherryblossom-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Halifax:20231102T130000
DTEND;TZID=America/Halifax:20231102T140000
DTSTAMP:20260410T181604
CREATED:20231026T114748Z
LAST-MODIFIED:20241024T182945Z
UID:10000695-1698930000-1698933600@staging.digitalinsights.supremeclients.com
SUMMARY:The epididymis: Balancing the burden and responsibility of fertility
DESCRIPTION:The responsibility of fertility is disproportionately placed on women\, who bear most of the health\, emotional and financial burdens. Infertility is rapidly rising\, with one in six Australian couples seeking assisted reproductive technologies to help them start a family\, and over 50% of cases involving a male factor. Despite these contributions\, we still don’t fully understand the mechanisms that create competent sperm for fertilization\, which occurs during their transit from the epididymis\, a highly specialized region of the male reproductive tract. \nTo address this knowledge gap\, we used high-resolution tandem mass spectrometry and in-silico analyses to characterize proteome-wide changes in mouse sperm. We studied changes associated with their transit through the epididymis and elicited in response to capacitation stimuli\, such as maturation initiated upon contact with the female reproductive tract. \nIn this webinar\, you’ll learn about: \n\nThe unprecedented depth of >6000 proteins and 14\,586 site-specific phosphorylation events across these sperm populations that we discovered using QIAGEN Ingenuity Pathway Analysis (IPA)\nHow sperm shed over 56% of their proteins during this process\, producing a refined fertilization-competent cell\nHow this reduced proteomic complexity of sperm coincides with the activation of certain functions\, such as sperm motility and capacitation\nKey proteins and kinases we identified through selective pharmacological inhibition that regulate sperm function\nThe role of RHOA on mature spermatozoa to reduce the rate of acrosome reaction by about 40%\n\nOur data represent an essential paradigm shift in our understanding of male fertility regulation. They will contribute to important advancements in developing non-hormonal male contraceptives and robust sperm selection biomarkers for infertile men.
URL:https://staging.digitalinsights.supremeclients.com/webinars-and-events/the-epididymis-balancing-the-burden-and-responsibility-of-fertility/
LOCATION:Virtual Global Event (Times shown in EST)
CATEGORIES:Discovery,Webinar
ATTACH;FMTTYPE=image/jpeg:https://staging.digitalinsights.supremeclients.com/wp-content/uploads/2024/05/S_1233_1_QDI_QDI_IPA_AOP_16x9_63871_Large-1200px.jpg
END:VEVENT
END:VCALENDAR