{"id":153359,"date":"2024-06-20T13:37:50","date_gmt":"2024-06-20T13:37:50","guid":{"rendered":"https:\/\/staging.digitalinsights.supremeclients.com\/plugins\/advanced-structural-variant-detection-free-plugin\/"},"modified":"2024-06-20T13:40:48","modified_gmt":"2024-06-20T13:40:48","slug":"advanced-structural-variant-detection","status":"publish","type":"plugin","link":"https:\/\/staging.digitalinsights.supremeclients.com\/ja\/plugins\/advanced-structural-variant-detection\/","title":{"rendered":"Advanced Structural Variant Detection (free plugin)"},"content":{"rendered":"<h1>Advanced Structural Variant Detection<\/h1>\n<p>The Advanced Structural Variant Detection (beta) plugin to the <a href=\"https:\/\/digitalinsights.qiagen.com\/products-overview\/analysis-and-visualization\/qiagen-clc-genomics-workbench\/\">CLC Genomics Workbench<\/a> is designed to identify structural variants based on combined evidence from unaligned read ends and coverage information of Whole Genome Sequencing (WGS) read mappings. It detects SVs with higher sensitivity and precision than the existing InDels and Structural Variants tool in the standard CLC Genomics Workbench toolbox.<\/p>\n<p>The plugin is simple to use: just install and run on a whole genome sequencing read mapping from within the Workbench.<\/p>\n<p>Known limitations:<\/p>\n<ul>\n<li>The plugin is not intended for use on long read data, targeted panel data, or RNA-seq data.<\/li>\n<li>Samples must have a well-defined ploidy \u2013 the detection of somatic variants is not explicitly supported.<\/li>\n<\/ul>\n<p>Note that this plugin is in beta.<\/p>\n<p>Check out <a href=\"https:\/\/digitalinsights.qiagen.com\/news\/blog\/discovery\/structural-variant-detection-using-clc-genomics-workbench\/\">this blog with performance benchmarks of this plugin.<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-20093 alignleft\" src=\"\/wp-content\/uploads\/2019\/02\/Advanced_Structural_3407bp_Deletion-1140x439.jpg\" alt=\"\" width=\"796\" height=\"307\"><\/p>\n<p><strong>Figure 1<\/strong>. A genome track view of a read mapping and a 3407 bp long deletion identified with the Advanced Structural Variant Detection (beta) plugin.<\/p>\n","protected":false},"featured_media":0,"parent":0,"template":"","class_list":["post-153359","plugin","type-plugin","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Advanced Structural Variant Detection (free plugin) - Bioinformatics Software | QIAGEN Digital Insights<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Advanced Structural Variant Detection (free plugin) - Bioinformatics Software | QIAGEN Digital Insights\" \/>\n<meta property=\"og:description\" content=\"Advanced Structural Variant De [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"http:\/\/staging.digitalinsights.supremeclients.com\/plugins\/advanced-structural-variant-detection\/\" \/>\n<meta property=\"og:site_name\" content=\"Bioinformatics Software | QIAGEN Digital Insights\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-20T13:40:48+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data1\" content=\"1\u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/plugins\\\/advanced-structural-variant-detection\\\/\",\"url\":\"http:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/plugins\\\/advanced-structural-variant-detection\\\/\",\"name\":\"Advanced Structural Variant Detection (free plugin) - Bioinformatics Software | QIAGEN Digital Insights\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/#website\"},\"datePublished\":\"2024-06-20T13:37:50+00:00\",\"dateModified\":\"2024-06-20T13:40:48+00:00\",\"breadcrumb\":{\"@id\":\"http:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/plugins\\\/advanced-structural-variant-detection\\\/#breadcrumb\"},\"inLanguage\":\"ja\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/plugins\\\/advanced-structural-variant-detection\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/plugins\\\/advanced-structural-variant-detection\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/ja\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Advanced Structural Variant Detection (free plugin)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/#website\",\"url\":\"https:\\\/\\\/staging.digitalinsights.supremeclients.com\\\/\",\"name\":\"Bioinformatics Software | QIAGEN Digital Insights\",\"description\":\"World-class software, services, content, and data insights for life sciences, pharma R&amp;D, precision medicine, clinical trials, healthcare, and genomics research organizations. 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